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The postulated effects of glutathione on pigmentation were an accidental discovery when skin whitening was observed as a side effect of high doses of glutathione

It is a designation used primarily by the FDA (Food and Drug Administration) for products, often in vitro diagnostic (IVD) components like reagents or instruments, that are in the laboratory research phase of development and are not intended for clinical diagnostic use

10.1016/j.bbi.2010.12.008 28 BhandariR.KuhadA.KuhadA

GL2 , a homeobox family gene that encodes the HD-ZIP IV transcription factor, plays an essential role in and is expressed throughout trichome development (Rerie et al., 1994