interaction of chloroacetamide electrophiles with cellular glutathion Selective covalent targeting GPX4 using masked nitrile-oxide Targeting a Therapy-Resistant Cancer Cell

Targeting a Therapy Resistant Cancer Cell State Using Masked Electrophiles as GPX4 Inhibitors bioRxiv Design, synthesis, and biological evaluation of nitroisoxazole containing spiro[pyrrolidin oxindole] derivatives as novel glutathione peroxidase 4 mouse double minute 2 dual inhibitors that inhibit breast adenocarcinoma cell proliferation ScienceDirect Structural and mechanistic analysis of covalent ligands targeting the RNA binding protein NONO: Cell Chemical Biology Discovery of novel benzylaniline derivatives containing chloroacetamide as GPX4 inhibitors with potential efficacy in triple negative breast cancer ScienceDirect Delineating cysteine reactive compound modulation of cellular proteostasis processes Nature Chemical Biology

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