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Endocannabinoids such as AEA are also known to mediate some of their cellular responses by targeting the non-selective cation channel TRPV1, whose activation has been linked to increased ROS production, AEA has also been reported to target the PPAR family of nuclear receptors, whose activation is known to induce the expression of antioxidant enzymes, including catalase and glutathione peroxidase 3 [5]

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Therefore, we investigated the genetic activity of hexokinase in mouse kidney tissues (Figure 1F)

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