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Conversely, metabolic dysregulation (including impaired AMPK activity and altered GLUT2-related pathways) has been linked to reduced expression of tight-junction proteins and barrier weakening [791,792]

After the immersion with the blocking buffer (10 mM Tris-HCl, pH 7.4, containing 0.5 M NaCl, 5% skim milk, and 0.5% Tween-20), the membrane was incubated with anti-APAP pAbs, anti-CYP1A2 pAbs, anti-CYP2E1 pAbs, anti-CYP3A pAbs, or anti- -actin pAbs at 4C overnight

2024ZYZD006), The Science and Technology Research Program of Chongqing Municipal Education Commission (Grant No

The amount of NAC required to counteract acetaminophen toxicity is determined by plotting the concentration of acetaminophen in plasma against the time post-overdose on a nomogram [28]