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2017;doi:10.1016/j.ejca.2016.12.001

shRNAi, short hairpin RNA interference

Although the precise mechanisms for sex differences are not completely elucidated, the faster immune response of women, which protect them from initial infection and severity might be one important factor

Methods 63 , 209215

Alterations of the IEB allow the excessive passage of food and microbiota antigens which elicit immune activation involved in the pathogenesis of the intestinal and systemic disease (e.g., diabetes, obesity, non-alcoholic liver diseases)