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Key points to consider when interpreting the evidence: Most studies are short-term , typically lasting fewer than 12 weeks, making it difficult to assess long-term efficacy or safety Results appear more pronounced in older adults or individuals with obesity, compared to younger, healthy populations L-carnitine alone, without dietary or lifestyle changes , is unlikely to produce clinically meaningful weight loss Neither NICE nor the NHS recommends L-carnitine supplementation as part of any weight management pathway

Studies have demonstrated SASs ability to induce ferroptosis in diverse tumor cells, suggesting its potential as a combinatory treatment with other cancer therapies to enhance overall treatment effectiveness ( As an excitatory neurotransmitter that binds to both excitatory neurotransmitter binding sites and Cl - dependent cysteine- and cystine-inhibited transporter sites, the Xc-system facilitates the transfer of glutamate out of and cystine in

Lipids 32: 351358