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34, 35 The potential therapeutic role of L-carnitine has been reported both for AIDS and ischemia wherein apoptosis is also involved

Purkinje neurons coexist with specialized astrocytes (Bergman glia), which protect the neurons.Subjects with ASD have activated microglia [35], which export copious amounts of glutamate [42].Glutamate is a mitochondrial toxin [43-45], and is selectively toxic to neurons [46-48].Could glutamate be the cause of the mitochondrial dysfunction and selective Purkinje neuron degeneration observed in autism

In addition, above the Na + -binding site (in the cavity, toward the extracellular side) we observe a second density that we have modelled as a water molecule (Fig

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