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Using these tools will aid the precision of radiation therapy, minimizing the risks of radiation-induced toxicities and injuries, and making medical care more personalized (Herrera-Quintana et al., 2024)

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Therefore, the effect of SAMe supplementation has been widely explored in different cellular and animal models of HCC development [13,244,245,246,247,248], including preventing or reducing the occurrence and establishment of HCC foci, showing proapoptotic effects in the tumoral cells and angiogenesis decrease