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A drug is assumed to be uniformly distributed within a compartment and can move dynamically in and out of compartments

10.1016/j.jhepr.2020.100218 JHEP Rep

Glutathione was chosen for its ability to enhance biocompatibility and cellular uptake

Metabolic re-programming in Notch-activated T-ALL by mTOR inhibitor AZD2014 combined with L-Asparaginase

APAP-induced liver injury is associated with glutathione depletion, the formation of APAP protein adducts, the generation of reactive oxygen and nitrogen species and mitochondrial injury