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References References Pickart, L., & Margolina, A

doi: 10.1016/j.forsciint.2014.10.025

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Promote renal calcium reabsorption Renal tubular calcium transport: upregulate the expression of renal tubular calcium channel (TRPV5), reduce urinary calcium excretion by 30% -40%, increase blood calcium concentration, and increase bone calcium deposition Evidence from preclinical studies on AOD 9604 bone protection (animal experiments) Postmenopausal osteoporosis (OVX rat model) Experimental Design: Animal: 6-month-old female SD rats underwent bilateral ovariectomy (OVX) to establish a postmenopausal osteoporosis model