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Jian Deng, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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How vitamin B12 deficiency in men over 50 impacts legs, feet, and sleep Numbness and tingling in the legs and feet One of the earliest signs of vitamin B12 deficiency is numbness or tingling in the legs and feet

The use of low dose naltrexone (LDN) can be an effective treatment for some autoimmune diseases, pain syndromes, and chronic fatigue syndrome