tripeptide glutathione structure L-444: Chemistry of Glutathione and

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In HCC, ERS is implicated in tumor cell proliferation, migration, invasion, angiogenesis, and resistance to chemotherapy

The peptide consists of three amino acidsglycine, histidine, and lysinein precise coordination with a copper ion, creating a bioactive complex with remarkable biological activities across diverse physiological systems

Once activated, they express -smooth muscle actin (-SMA) and synthesize collagen, as well as other extracellular matrix proteins, such as fibronectin [11]

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