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Such heterogeneity complicates the development of universally effective therapies and underscores the need for personalized approaches, which currently face limitations due to an incomplete understanding of these individual determinants (164)

Proc Natl Acad Sci USA 94:1110211107 Takahashi H, Watanabe-Takahashi A, Smith FW, Blake-Kalff M, Hawkesford MJ, Saito K (2000) The roles of three functional sulphate transporters involved in uptake and translocation of sulphate in Arabidopsis thaliana