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doi:10.1111/j.1471-4159.2006.03693.x What is DSIP (10mg)

While classical antifolates like methotrexate inhibit DHFR and nucleotide synthesis [164], recent drug development has expanded to other key enzymes such as MTHFD2, PHGDH, and SHMT2, with inhibitors now in clinical or preclinical development, as summarized in Table 1