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Klein Geltink RI, Edwards-Hicks J, Apostolova P, OSullivan D, Sanin DE, Patterson AE, et al

Jul 4 2023;12(13):e029852

A serum APAP concentration (measured at least 4 hours after ingestion) resulting in a value above the lower line of the nomogram necessitates a full course of NAC therapy (eg, standard oral loading dose of 140 mg/kg of NAC followed by 70 mg/kg every 4 hours for 17 oral doses) be delivered

Erastin, Sorafenib, RSL3, and FIN56 are common inducers of ferroptosis, while deferoxamine, Ferrostatin-1 (Fer-1), and Liproxstatin-1 (Lip-1) are common inhibitors of this process

De novo expression of parvalbumin in ependymal cells in response to brain injury promotes ependymal remodeling and wound repair