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Metformin, an antidiabetic drug, inhibits the cAMP/CREB/MITF axis leading to the downregulation of the expression of tyrosinase, Tyrp1 and Tyrp2, and ultimately to the decrease of melanin production [99]

doi: 10.1016/B978-0-12-816155-5.00008-7 15 AnagnostopoulosC.CharalampousA

Ischemic stroke can be converted to haemorrhagic stroke due to multiple factors such as ROS and inflammation (Shao et al

One has to keep in mind, however, that in contrast to the short duration of the murine hair cycle studied here, the anagen phase of human scalp hair lasts for several years (3) and might show a different sensitivity to reduced vascularization

Aoyama K, Matsumura N, Watabe M, Wang F, Kikuchi-Utsumi K, Nakaki T