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Interestingly, numerous small vesicles (~30 to 50 nm in diameter) were observed near MVBs (Fig

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On the other hand, dysregulation of neuro-inflammatory processes in the dorsal root ganglia, axons, and spinal cord, including the dysregulation of cytokine and chemokine levels, increased presence and activation of immune cells, and activation of neuronal accessory cells, has been associated with CIPN pathology