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In the neurogenic niche, astrocytes express ciliary neurotrophic factor (CNTF), while the receptor, CNTFR, is predominantly expressed in neural progenitor cells and hippocampal neurons [22]

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3.5 FXR-TonEBP axis was enhanced after water deprivation challenge in a normal state, but this compensatory protective response blunted in DM Immunofluorescence analysis revealed that water deprivation significantly increased FXR expression in the control water deprivation group, whereas this upregulation was less pronounced in the DM water deprivation group (Figure 4A,C)