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MSC-EVs have been investigated across a broad spectrum of preclinical and clinical applications, including tissue regeneration, immune-related disorders such as graft-versus-host disease (GvHD), rheumatoid arthritis, and inflammatory bowel disease (IBD), as well as neurological conditions, pulmonary and liver diseases, oncology, anti-aging therapies, dermatological treatments, and even vaccine delivery systems

Vitamin K deficiency: an emerging player in the pathogenesis of vascular calcification and an iatrogenic consequence of therapies in advanced renal disease

[Note: Patients who have had a partial or total gastrectomy become IF deficient and, therefore, B 12 deficient.] Individuals with cobalamin deficiency are usually anemic, and they show neuropsychiatric symptoms later, as the disease develops

Biochim Biophys Acta 1979