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A decline in PRPP could bottleneck the ability of the liver to generate NAD + from NA or NAM

[DOI] [PubMed] [Google Scholar] 129.Refolo LM, Pappolla MA, Malester B, LaFrancois J, Bryant-Thomas T, Wang R, Tint GS, Sambamurti K, and Duff K

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Menzel A, Samouda H, Dohet F, Loap S, Ellulu MS, Bohn T (2021) Common and novel markers for measuring inflammation and oxidative stress ex vivo in research and clinical practicewhich to use regarding disease outcomes