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Since cellular senescence is considered a natural defense mechanism against tumor development, and senescence inductions triggered by currently applied therapies can significantly impact their effectiveness, it is assumed that purposeful stimulation of senescence in cancer cells may be a promising direction in the development of anticancer therapy [8, 15, 55]

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The acute phase or mild inflammatory response In addition, we anticipated detecting elevated levels of positive APPs and decreased levels of negative APPs in the event that severe IMDD is indeed accompanied by IRS activation

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