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Hepatology 70 , 20182034 (2019)

Figure 3 The publications of TMAO and CVD come from 322 academic institutions

A 2023 meta-analysis found that NAC improved some metabolic markers in women with PCOS, including fasting glucose.21 More recent research has also explored NAC alongside ovulation-induction treatments, suggesting possible benefits for endocrine and reproductive outcomes.20 While the findings are encouraging, researchers are still working to determine which women are most likely to benefit and how NAC compares with established treatments such as metformin

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Several miRNAs have been described as regulators of these processes ( Table 2C )