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Inhibition of fat production AOD 9604 inhibits adipogenesis through the following mechanisms: Inhibition of adipocyte differentiation: AOD 9604 can down-regulate the expression of peroxisome proliferator-activated receptor (PPAR) and CCAAT/ enhancer binding protein (C/EBP), and block the differentiation of preadipocytes into mature adipocytes

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Because NNMT intersects NAD salvage, pairing with NMN/NR is a common experimental strategy to test additive or synergistic effects on cellular NAD and metabolic endpoints

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