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Although considered reasonably safe, AF puncture has been shown to promote IDD as well as to increase the risk of disc herniation and endplate changes both in preclinical 16 and clinical studies

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Biol Trace Elem Res 168(2):411420 Hopps E, Noto D, Caimi G, Averna MR (2010) A novel component of the metabolic syndrome: the oxidative stress