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If you are deficient in B12, a course of injections or high dose oral supplementation may be advised

Combined oral and enema treatment with Pentasa (mesalazine) is superior to oral therapy alone in patients with extensive mild/moderate active ulcerative colitis: a randomised, double blind, placebo controlled study

However, in Be(2)-C cells, it reduced ATP content by more than half ( Figure 3D ) without increasing cell death ( Figure 4A ), indicating a cytostatic rather than cytotoxic effect

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The NHS route is for people with a clinically confirmed B12 deficiency