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However, in mice pretreated for 5 d with CTR0066101 and challenged with glucagon, hepatic Tyr levels were not affected compared with the control animals (Fig 4I)

Microbial size, the presence of virulence factors, defects in host barrier integrity, along with the active uptake and presentation of luminal antigens by cells of the intestinal epithelium are among the factors that contribute to bacterial translocation (Wolochow et al