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To address this deficiency, selenite (along with iodine) or Se-yeast is added to salt or maize flour, as in the eastern farming region of China, where there is a Se-poor geographical belt [106]

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Ferroptosis contributes to follicular depletion, ultimately leading to DOR (Figure 4B)

Hence, the intracellular redox state, which is characterized by the levels and ratios of oxidized (GSSG) and reduced (GSH) glutathione, is regarded as a significant indication of the cellular health (Lu 2013)