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3 Transcriptional response to cysteine deficiency

XO has been shown to underlie the development of hypertension-induced end-organ damage (156)

This patent introduces oxidative stress environments (HO) commonly found in specific pathological tissues (such as tumors, inflammation, or atherosclerotic plaques) as a trigger, offering a more intelligent and fluorescently traceable response mechanism compared to the widely used environmental factors like pH and temperature

Nicotinamide adenine dinucleotide metabolism in the immune response, autoimmunity and inflammageing. British journal of pharmacology 179.9 (2022): 1839-1856

doi: 10.1007/s10571-023-01388-8 36 WangBWangYZhangJHuCJiangJLiYet al