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Prostate 80 , 481490 (2020)

Its expression and active state can be upregulated by the glucocorticoid dexamethasone (Filla et al., 2011

Evason K, Collins JJ, Huang C, Hughes S, Kornfeld K

Previous structural studies have uncovered the open and closed conformations of ME2, which correspond to the enzymes inactive and active states, respectively