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Description

Blood tests like serum iron or ferritin are nonspecific, and no FDA-approved companion diagnostic exists to detect ferroptotic activity in cardiovascular disease

The study population were adults with obesity or overweight with at least 1 weight-related comorbidity but without diabetes

Two milliliters of the supernatant were mixed with 2 mL glacial acetic acid and 2 mL acid ninhydrin, then incubated for 1 h at 100 C

Furthermore, glutathione levels, catalase, superoxide dismutase, glutathione transferase and glutathione peroxidase activities were significantly decreased