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Moreover, it has been noted that female subjects seem to have greater protection against the adverse effects of lipo-toxicity caused by dysfunctional adipose tissue, probably through a differentiated expression of sex-dependent genes involved in adipogenesis (Figure 2) [58,82,83]

Augustin Fliche, Cedex 5, Montpellier 34295, France., Montpellier, France, 3 Department of Biostatistics, CHU LILLE, Lille, France, 4 Cooper neurological institute, Camden, United States Background and Aims: The efficacy of endovascular thrombectomy (EVT) in patients with largest ischemic strokes (ASPECTS 0-2) remains debated

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Conversely, Jahrami et al