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TB-500 complements these effects by enhancing cell migration, improving tissue flexibility, and increasing nutrient delivery through new blood vessel formation

Of these, the latter two hypotheses have been recently mathematically examined to have identical calcium-dependent dynamics which provides strong theoretical evidence for a calcium-based model of plasticity, which in a linear model where the total number of receptors are conserved looks like where is the synaptic weight of the th input axon, is the concentration of calcium, is a time constant dependent on the insertion and removal rates of neurotransmitter receptors, which is dependent on , and is also a function of the concentration of calcium that depends linearly on the number of receptors on the membrane of the neuron at some fixed point

10.1021/acsabm.4c00112 78 FriedliM

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