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Using patch clamp electrophysiology, the researchers showed that curcumin potentiated 7-nAChRs in rat hippocampal neurons, and also restored SOD and CAT activity interactions (Jayaprakash et al., 2021)

The pathophysiology is incompletely understood, but decreased FAO of the placenta and fetus are likely to cause accumulation of long-chain 3-hydroxyacyl fatty acid metabolites in the maternal circulation

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Additionally, 1030% of patients of those who are resistant to the effects of antidepressants and thus non-responders to treatment