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Dutasteride blocks DHT more completely than finasteride (it inhibits both type I and type II 5-alpha reductase)

Examining genes relevant to ventricular hypertrophy upregulated in AC5 transgenic hearts even at baseline, transcription factor binding analysis revealed enrichment for the binding sites of nuclear factor of activated T-cells (NFAT), vital for the development and progress of cardiomyocyte hypertrophy (Park et al., 2011)