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Representative participants: The Nature's Bounty Co

doi: 10.2141/jpsa.0150133 280

The downregulation of HDAC5 expression with RNA interference can improve renal tubular injury by upregulating the expression of KLF2 and inhibiting the expression of NALP3 in a sodium oxalate-induced acute oxalate nephropathy mouse model

Zhao et al., 2020)

Persons who have had a previous NTD-affected pregnancy or considered high-risk due to other factors (e.g., use of certain medications, family history) may be advised to consume up to 5,000 micrograms/day of folic acid when they are planning to become pregnant