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Brain 142 , 31583175 (2019)

In macrophages, for example, lactylation of proteins such as Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta (IB) enhances their stability or transcriptional co-activator capacity, thereby boosting the production of cytokines like IL-6 and IL-12 (58)

This relates to the Arg paradox, a phenomenon where exogenous L-Arg leads to NO-mediated biological effects even though NOS, which utilizes L-Arg as a substrate, is saturated (161)

doi: 10.1016/j.euroneuro.2015.12.039

Comparing two extracellular additives to facilitate extended storage of red blood cells in a supercooled state