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10.1016/j.krcp.2015.12.003 24 Conglei PanH

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In this review, we retrace the research history of TGF- and introduce the molecular mechanisms regarding its biosynthesis, activation, and signal transduction

The National Cancer Institute conducted chemoinformatics analysis of 60 cell lines and showed a negative correlation between xCT expression levels and sensitivity to compounds associated with GSH-mediated resistance, which indicated that xCT expression induces chemoresistance via GSH-mediated ROS detoxification activity (82)

Results: Breast cancer can be broadly classified into major molecular subtypes i.e., triple-negative breast cancers, Luminal A, Luminal B, and HER2-enriched