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B12 injection shots can usually be felt within 24 hours (and a change should show in blood tests after a month or two) A high dose of B12 oral supplementation takes the same time as an injection: roughly 24 hours to feel an improvement and then up to 2 months to show in blood markers

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2024 Nov 24;12(11):e009805

Emerging evidence indicates that insufficient maternal folate levels during pregnancy may increase the risk of ASD in offspring, whereas folate supplementation has been associated with reduced neurotoxicity, enhanced neurodevelopment, and attenuation of ASD-related symptoms ( 4.4 Trace elements and nutritional supplementation Children with ASD commonly exhibit elevated oxidative stress, characterized by a reduced glutathione-to-oxidized glutathione (GSH/GSSG) ratio and increased levels of malondialdehyde (MDA), a marker of lipid peroxidation (Lee et al., 2021