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Description

PMID: 8833620

This concept is experimentally supported by models in which neomycin treatment increased the abundance of Bacteroidetes in rat lungs by 2.5-fold and elevated LPS levels, which in turn alleviated EAE by promoting microglial type I interferon production [14]

doi: 10.1002/cbin.12229 60 XuYYangZDaiTXueXXiaDFengZet al

Because of the many functions that the gut microbiota fulfills, compelling evidence suggest that gut microbiota dysregulation could be directly associated with low-grade inflammation and a wide range of pathological conditions including obesity and metabolic disorders like type 2 diabetes [64, 65], inflammatory bowel disease (IBD) [66], gastrointestinal cancer [67] and psychiatric disorders, including BD [68]