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PLoS One 13:e0190205

Oxidative stress is caused by an alteration of the prooxidant/antioxidant balance that results in the production and accumulation of ROS

Regulation of glucose metabolism by DNA methylation In TC, DNA methylation profoundly reshapes glucose metabolism through a multi-level regulatory network, which not only directly epigenetically regulates metabolic genes, but also indirectly affects key signaling pathways (Fig