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Vegans or strict vegetarian diets can be at particular risk of developing a deficiency as non-animal sources of food usually contain no or very low doses of B12

AdoCbl binding allosterically affects BV affinity, with the BV dissociation constant decreasing ~10-fold from K d ~ 7 M to ~0.7 M in the presence of AdoCbl (Fig

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or The athlete used a substance/medication/method out-of-competition that is prohibited in-competition only