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AJR Am J Roentgenol 197(6):W1060-6, 2011

Ralston NV, Raymond LJ

We found that the XCI gene-ACSL4 is upregulated in SS and downregulated following genistein treatment

BPC-157 Supports Vascular and Neurological Repair One underappreciated hallmark of long COVID is endothelial dysfunction damage to the lining of blood vessels that impairs circulation, oxygenation, and tissue delivery.7 BPC-157 has demonstrated angiogenic (new blood vessel formation) effects in research models, upregulating VEGFR2 and promoting collateral circulation in ischemic tissue.8 This matters for two reasons: Cardiovascular symptoms (breathlessness, reduced exercise tolerance, tachycardia) may partly reflect impaired tissue oxygenation from vascular damage Neurological symptoms (brain fog, cognitive impairment) may similarly reflect reduced cerebral blood flow BPC-157's neuroprotective effects shown across models of traumatic brain injury, dopamine dysregulation, and serotonin syndrome also suggest value in supporting the neurotransmitter disruption many long COVID patients experience.9 BPC-157 Modulates Inflammation Without Immune Suppression This is critical

Specifically, glutathione helps shift melanin synthesis from darker eumelanin to lighter pheomelanin , resulting in a gradual lightening of the skin over time