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J Am Soc Nephrol 2002;13:708-14

Ongoing conversations between parents and pediatricians about energy drinks are essential in order to maintain our childrens overall health and well-being. Resources: Energy Drinks | Healthy Schools | CDC Spilling the Beans: How Much Caffeine is Too Much

Additionally, BTX may exhibit anti-nociceptive properties by down-regulating voltage-gated sodium channels, as demonstrated in a rat model of trigeminal neuralgia, or by diminishing the peripheral release of neurotransmitters such as substance P and CGRP, along with the pro-inflammatory cytokine IL-1 (101103)

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Maternal autoimmune diseases have been suggested as a trigger for developmental central nervous system deficiencies as well as ASD (Han et al., 2021)