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10.1002/jbt.21682 22 HensleyK.KotakeY.SangH.PyeQ

Depletion of L-arginine induces autophagy as a cytoprotective response to endoplasmic reticulum stress in human T lymphocytes

That is normal and part of adaptation, but more serious strains or repeated overuse can interrupt training for weeks

These cells rely on dietary lipids to promote metastasis, and blocking CD36 significantly inhibited lymph node metastasis, underscoring the critical role of lipid metabolism in the metastatic process (148)