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Consistently, a recent long-term cohort study in hospital NS workers using a 1-1-3 rotating schedule reported significantly increased serum and urinary levels of 8-OHdG during the NS period, which remained elevated even one month after returning to DS, indicating persistent oxidative DNA damage induced by chronic NSW 69

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The elevated cardiovascular risk observed in individuals with diabetes results from a multifactorial interaction that involves both classical risk factors, such as dyslipidemia and hypertension, and non-traditional contributors linked to the development of atherosclerosis