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5.3 Lung cancer and pancreatic cancer T-bet exhibits dual roles in lung cancer: it promotes lung adenocarcinoma progression by maintaining tumor stemness and activating the T-bet-IL-4 signaling pathway, while simultaneously being highly expressed in TAA-specific tumor-infiltrating Treg (TIL-Treg) within the tumor microenvironment, potentially contributing to antitumor immune responses

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To establish a causal link between gut microbiota composition and hepatic Snhg9 expression, we performed fecal microbiota transplantation (FMT) from Facility A or B donors into antibiotic-pretreated recipients