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Mitochondrial aconitase activity was measured by NADPH coupled conversion of citrate to isocitrate in the presence of isocitrate dehydrogenase using the Bioxytech Aconitase-340 assay kit

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doi: 10.21037/jgo.2019.03.14 19

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Roffman JL, Petruzzi LJ, Tanner AS, et al

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Once inside the cell, cisplatin becomes activated by the substitution of one or two chloride atoms by water, a process known as aquation

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