chac1 er stress glutathione degradation of enhances cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells via the GCN2-eIF2α-ATF4 pathway A scheme of the mechanism
A scheme of the mechanism of CHAC1 degradation of glutathione enhancing Download Scientific Diagram CHAC1: a master regulator of oxidative stress and ferroptosis in human diseases and cancers PMC Glutathione (GSH) depletion by ChaC1 results in a more oxidizing Download Scientific Diagram Molecular Medicine Reports Human CHAC1 Protein Degrades Glutathione, and mRNA Induction Is Regulated by the Transcription Factors ATF4 and ATF3 and a Bipartite ATF CRE Regulatory Element* Journal of Biological Chemistry
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