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Huang Y

P.da Silva GesteiraA.MicheliF.et al

Role of H 2 S in MCT-induced PH MCT, a toxic alkaloid, induces the proliferation of pulmonary VSMCs and inflammation of endothelial cells, leading to right heart dysfunction due to cardiac overload

This observation is further supported by steady-state clearance measurements in dogs, in which C I /GFR was found to increase in response to hydrochlorothiazide-induced diuresis, and to be lower, near that of C Cl /GFR, in dogs that had been maintained on a sodium deprivation diet (Beyer et al