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While more convenient and non-invasive, its safety and effectiveness are still under investigation and not established

Figure 5 Wnt/-catenin pathway markers, steroid excess and survival When classifying tumours as secreting excess of GC only (GC, Figure 6A ), GC together with androgens and precursors (GCA, Supplementary Figure S3 ) or being hormonally inactive, the proportion of GC-secreting tumours with strong LEF-1 expression (n=9/17) was higher compared to inactive tumours (n=5/17) or tumours with excess of multiple steroid hormones (n=3/17), however without statistical significance (p=0.0780)

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Insulin is secreted primarily from pancreatic beta cells in proportion to blood glucose levels and is best known for promoting glucose uptake in insulin-responsive metabolic cells and tissues 1